This has carbon in it and is best taken at bedtime as it will pull out all the minerals it contacts so it is best taken alone or before and after having to receive immunization shots. This formula specifically helps to remove toxins from your bile in the intestines before you can re-absorb the toxins when the bile is re-absorbed each night. This is best used with the GCEL intracellular Glutathione blend. It can also be added to all detoxification protocols. The FDA has not approved of these statements and you are taking this herbal remedy, that has some laxative qualities about it, at your own risk usually at bedtime. Contians magnesium, charcoal-activated carbon, humic acid, apple fiber, cascara sagrada, dong quai herb, cinquefoil herb and more.